7 Best Running Shoes for Neuropathy [2024 Upd.] Top Choices

 Last Updated on July, 2024

You know how the damage of peripheral nerves causes neuropathy.

But on the flip side, staying indoors without exercising when you’re battling neuropathy doesn’t make anything better. After all, being healthy is an even higher priority when you have a condition like this.

What about the pain in the legs? That’s the real problem, isn’t it?

For your luck, there are so many running shoes made EXPLICITLY for neuropathic feet. But how can you choose the best?

That’s where I come in.

Editor’s Choice
Orthofeet Lava (Men)
Arch support
Toe box







Overall Score


#2nd Best Choice
Orthofeet Coral (Women)
Arch support
Toe box







Overall Score


#3rd Best Choice
Kuru Atom Wide
Arch support
Toe box







Overall Score


Why Trust Me?

I chose about 15 running shoes for neuropathy and other neuropathy shoes and tested them with the help of people with neuropathy. After assessing the features, it wasn’t challenging to rank them.

This read has the seven best running shoes for neuropathy, and I’m sure you’ll find your preference right here. 

Let’s begin!

Top 7 Best Running Shoes for Neuropathy

1. Orthofeet Lava (For Men)

As you may already know, Orthofeet is the preferred go-to brand for most people battling neuropathy. Their Lava no-tie shoe is the best running shoe for neuropathic feet.

Many people with neuropathy have heel pain or deformities, such as hammertoes or bunions, making it difficult to find shoes that fit comfortably. The wide toe box of the Orthofeet Lava running shoes provides extra room for the toes, which can help to reduce pressure on the feet and toes.

In addition to the wide toe box, these shoes also have a cushioned insole and a lightweight sole that can help to absorb shock and provide additional support. It is supported by the insole made of a soft, multi-layer foam that molds to the foot’s contours.

So far, these shoes are absolutely perfect for neuropathic feet.

The shoe features a lightweight rubber sole designed to absorb shock when running. Its heel cushion will help you more with the anatomical arch support.

The breathable material of the knitted upper allows air to circulate the foot, helping maintain the coolness of the feet during running. There’s also an anti-microbial fabric to battle against sweat-based bacteria.

It also has a soft, smooth interior with extra foam padding — that’s extra comfort when running for extended periods.

The upper is also designed with a non-binding construction, which does not put pressure on the foot, reducing the risk of blisters or other injuries. 

On top of all that, the adjustable lace eliminates the tedious need to tie up laces providing easy on/off wear. 

You can get the shoe between men’s sizes 7 and 14; the size chart is for your reference.

The rule of thumb for anything medical is to buy them from the manufacturer’s official website. Will you be thrilled to hear that you get $15 off of your order when you do?

That’s in addition to free returns, free premium orthotic insoles, and free USPS ground shipping.

All these features make these the best running shoes for neuropathy.


  • Protective toe box reduces pressure on the feet and toes
  • Cushioned insole provides customized support and cushioning
  • Lightweight sole reduces the impact on feet and legs during exercise
  • Breathable upper to maintain temperature
  • Non-binding construction reduces the risk of blisters or other injuries
  • Excellent arch support for improved balance 
  • Seamless lining for friction reduction 
  • Can accommodate custom orthotics 
  • 60-day money back guarantee 


  • Limited color options

2. Orthofeet Coral (For Women)

When Orthofeet has Lava for men, Coral is the best solution for female neuropathic feet.

You will notice several similarities between Lava and Coral as we go, emphasizing the Orthofeet design quality.

The Orthofeet Coral shoes feature a lightweight, ergonomic design that provides excellent support and cushioning for the feet. The shoes have a non-binding, padded interior that reduces pressure on the feet, making them ideal for running when you have sensitive neuropathic feet.

The shoes also have an extra-depth design, which provides more room for the toes and helps prevent blisters and other foot injuries.

Contoured anatomical orthotic sole in the Coral is quite helpful to distribute weight evenly across the feet, reducing pressure and enhancing stability when running. 

Did I mention its non-binding uppers with extra depth design? You know how it increases overall comfort. That comfort only increases with the foam padding with extra depth design in the toe area.

All that makes it heavenly not only while running but walking too. 

The mesh upper, similar to the Orthofeet Lava, is made from a breathable fabric. That’ll take care of your feet’s sweat buildup too.

It also has an anti-microbial fabric that safeguards your running feet from bacterial building up, similar to Orthofeet Lava. 

Coral’s multi-layer Ortho-cushion system features a shock-absorbing insole that reduces pressure on the feet. This feature can be particularly beneficial when running, as it helps protect the feet from impact and reduces the risk of injury.

You can also replace the soles as you wish.

Orthofeet Coral comes in women’s sizes from 5 to 12, with a size and fit chart similar to the Orthofeet Lava. You can also decide its width from narrow to standard to wide and extra wide.

If you’re a woman (or know one) who has neuropathic feet and wants to run safely, these are the best shoes for that.


  • Ergonomic design for female feet
  • Great cushioning and support
  • Alleviates overall foot pain
  • Lightweight and ergonomic design
  • Extra wide toe box
  • The ortho-Cushion system absorbs shock and reduces pressure
  • Mesh upper helps keep feet cool and dry
  • The extra-depth design provides more room for toes
  • Contoured sole ensures a better bit


  • Bungee lace design may not be for everyone

3. Kuru Atom Wide

Designed with a range of features, the Kuru Atom Wide shoe is ideal for brave men who want to stay active while dealing with the challenges of neuropathy.

The Kutu Atom is built with a sturdy sole that offers excellent stability and helps to reduce foot fatigue. 

The sole also features a unique KuruSole technology designed to mold to the contours of the wearer’s foot. That provides a customized fit that helps to minimize pressure points.

The spacious design of the shoe is specifically designed to accommodate wider feet and toes. That’s how you can be safe from unnecessary friction between the toes and the inner fabric. 

Who wants blisters after every single run, anyway?

The Kuru Atom Wide shoe also features a breathable upper, which helps to keep feet cool and comfortable during runs. The upper is made from a lightweight mesh material designed to promote airflow. 

That’s how the shoe can prevent excess moisture buildup and reduce the risk of blisters or even odor.

The Kuru Atom Wide shoe is also designed with an anatomical footbed that provides excellent arch support and helps to promote proper alignment. 

Exceptional built-in arch support is the cherry on top, ensuring your feet properly hug the super-comfortable inner fabric. Not only can you slip them, but you can also use those laces to get the perfect fit.

And, no, this isn’t a laced shoe but a slip-on shoe with laces for minor adjustments.

On top of all that, you get to choose the Kuru Atom in four colors, including full black.


  • Provides excellent support and stability
  • Accommodates wider feet and toes
  • Breathable upper for added comfort
  • Anatomical footbed for proper alignment
  • Durable and slip-resistant outsole for good traction on various surfaces
  • Designed to reduce friction and pressure on feet


  • Even though wider, a little more wider toe box would’ve been great

4. Asics Gel-Nimbus® 24 Trail

So, what makes the ASICS Gel-Nimbus so special?

The gel cushioning system of the Gel-Nimbus 24 Trail shoe is designed to provide added support and shock absorption for the feet. The gel cushioning is located in the heel and forefoot areas. Both of which tend to experience the most impact while running.

For your luck, the Gel-Nimbus 24 Trail shoe has a wide-toe box. You know how it can help reduce pressure on the toes and prevent foot pain.

After all, it only gets intense when you run. With more space, the toes can move freely, and the risk of blisters or calluses can be minimized.

Its midsole is made from a trademarked lightweight material named FF BLAST™ (FLYTEFOAM BLAST) and has highly responsive cushioning and bounce. That’s why these are certified comfortable shoes.

The shoe’s outsole is made of durable rubber designed to be flexible, allowing the shoe to adapt to different terrain. That’s why you get extra support and stability on uneven surfaces. 

Its 3D SPACE CONSTRUCTION™ Improves compression and cushioning at footstrike and reduces pronation.

The upper of the Gel-Nimbus 24 Trail shoe is made of breathable mesh material that allows for adequate airflow to the feet. This can help prevent overheating and excessive sweating, which can be uncomfortable and potentially exacerbate neuropathic symptoms. 

The mesh material is also lightweight, making the shoe comfortable and breathable during long runs.

This shoe also features an Ortholite sock liner. The sock liner is designed to provide additional cushioning. That basically makes these impressive supportive shoes. 

You can include custom orthotics to handle severe neuropathy pain in these running shoes.

On top of that, you also get a traditional lace-up closure giving the best fit. For anyone who prefers laces, Gel-Numbul 24 is therapeutic footwear.


  • 3D space construction for improved compression 
  • FF blast highly comfortable cushioning 
  • Gel cushioning for support and shock absorption
  • Roomy toe box for reduced pressure on toes
  • Durable outsole for excellent traction
  • Breathable mesh upper for airflow
  • Ortholite sock liner for additional cushioning and support


  • May not provide enough support for severe neuropathy

5. Dr. Comfort Katy

If you’re a woman with neuropathic feet who’d like stylish shoes for running, you should probably read about the Dr. Comfort Katy shoes.

The no-tie elastic lace closure of these shoes is admirable. It makes it easy to put on and take off the shoe without worrying about tying laces or adjusting them throughout the run. 

This feature is especially helpful for those with difficulty tying laces or manipulating small parts. 

The insoles can be removed and replaced with custom orthotics or other inserts. That’s a good push to maintain foot health amazingly. It feels soft against your feet but has enough firmness underneath to provide support. 

The extra depth feature of the shoe is another benefit, providing more room in the toe box to accommodate swelling or any deformities in the feet. This feature helps to distribute the body’s weight evenly across the foot. 

That reduces pressure points and minimizes the risk of injury or discomfort during running.

The durable, non-slip sole provides excellent traction on various surfaces, allowing runners with neuropathy to maintain their balance and stability while running.

These shoes are made with breathable premium materials too. Now you know how breathability helps your feet get rid of sweat. The padded tongue and collar add extra comfort and prevent chafing, while the mesh upper provides excellent ventilation.

Dr. Comfort Katy women’s neuropathy shoes are lightweight by design. That’s why women love running in them. After all, why wear unnecessary heavy shoes when you have sensitive feet?

The shoe comes in sizes ranging from 6.5 to 11 with regular and wide fits. As mentioned, you can buy this beautiful shoe in either purple, green & turquoise, pink & blue, or turquoise. 


  • No-tie elastic lace closure for easy on/off
  • Removable insoles for customization
  • Extra-depth feature for more room in the toe box
  • Durable, non-slip sole for excellent traction
  • Breathable materials to keep feet dry and cool
  • Padded tongue and collar for added comfort
  • Lightweight design for running


  • Some users said reported that the shoe has durability issue

6. Comfort Jason

Like Orthofeet, Dr. Comfort has separate products for both men and women. Dr. Comfort’s Jason is their men’s shoe.

In fact, these shoes are specifically designed to provide the support and comfort necessary for individuals with foot conditions such as diabetes, arthritis, and plantar fasciitis. 

This lace-up design ensures a secure fit, reducing the risk of slipping or rubbing, which can cause discomfort or injury for individuals with sensitive feet. 

The cushioned footbed and roomy toe box offer ample protection and support for sensitive feet.

The lightweight and flexible outsole allows for a comfortable and natural stride. The shoes also have ample room for customized orthotics.

The shoes also feature a non-slip outsole, providing additional traction and stability while running. Needless to say, this design also helps individuals who may struggle with wearing shoes in the first place.

Moreover, the Dr. Comfort Jason shoes come in extra wide width and depth options, ensuring that individuals with larger or swollen feet can find a comfortable fit. You know how important it is when you’re running with ultra-sensitive feet.

Compared to the Dr. Comfort Katy shoes, which are designed for women and have a Mary Jane style, the Jason shoes are better suited for running due to their lace-up style. 

Both shoes offer similar features, such as cushioning and a roomy toe box. But the difference in style and sizing may impact.

Made from superior 3D technology adhering to the needs of neuropathic feet, these shoes will definitely have your back. 

Oh, it comes in black, red, and blue too!


  • Designed for individuals with neuropathic feet and foot conditions
  • Ample room for custom orthotics and a large toe box
  • Easy on/off closures and non-slip outsole
  • Extra wide width and depth options are available
  • Made using 3D technology for a precise and comfortable fit
  • Lightweight and flexible outsole
  • Cushioned footbed offers ample protection and support


  • Relatively more expensive 

7. Skechers Afterburn

As you might know already, Skechers is a brand recognized for providing the utmost comfort for neuropathic feet. The brand’s Afterburn shoes are the best recommendation for running.

For starters, its leather upper features durable synthetic overlays. It is complemented by mesh fabric panels. The combination of these features ensures the cooling of your feet, especially when you’re running and your feet are warmer.

Similar to most shoes on this list, the Skechers Afterburn also has a lace-up design. Now you know how it enables a better fit while making it extra easy to put on and take off. 

In addition, the padded heel collar of the shoes immensely increases the comfort of your sensitive feet.

The comfort further increases thanks to the padded tongue as well. You’d notice signature logo accents on the tongue, side, and firm heel counter.

The signature feature memory foam™ of Skechers is available in Afterburn shoes too. These foams let your feet sink into foam, and that’ll be the shape of it! The right shoes are made specifically for you.

In addition, the Articu-Lyte™ midsole is also beloved in the community for its shock-absorbing capacity. The flexibility of this part only makes it even more comfort-focused. 

The cherry on top is the flexible outsole that provides ideal traction. Too much friction will make running harder, and smoother outsoles can make you slip, and the Afterburners are the perfect balance shoes for that.

You also can get these shoes in five colors, including black. Considering all the features and benefits, these could be your new balance shoes when running, as a man who wants to maintain his health amidst challenges would admire.


  • Memory Foam™ insole for customized support and comfort
  • Articu-Lyte™ midsole for natural foot movement
  • Durable leather and synthetic upper with a breathable design
  • Suitable for running and high-impact activities
  • Stylish design with color options available


  • May not provide enough support for severe neuropathy
  • Memory Foam™ insole may wear down over time
  • Articu-Lyte™ midsole may not be as durable as marketed

Buying Guide — Best Running Shoes for Neuropathy

people running on the ground and wearing Neuropathy Shoes

Check for a Wide Toe Box

Look for shoes that has ample space for toes to move, reducing the likelihood of blisters and allowing better circulation. This will also prevent toes from rubbing against each other, which can be painful. Shoes from Orthofeet and Dr. Comfort do an excellent job in this area which roomy toe boxes allowing a lot of space for your toes to move.

See if They Work as Walking Shoes as Well

Choose running shoes that can double as walking shoes, providing additional benefits. This will ensure your feet remain comfortable and supported while performing low-impact exercises. Kuru Atom is a great alternative if you can’t find Orthofeet ones.

Evaluate the Arch Support 

Look for shoes with good arch support to distribute weight evenly. That alleviates discomfort and improves balance and stability.

All of the shoes in this list provide top-notch or at least good arch support in this list, you can’t go wrong with any.

Double Check the Correct Size

Measure your feet and choose shoes that fit correctly to prevent blisters and discomfort. Wearing ill-fitting shoes can cause pain and discomfort and lead to foot injuries. 

The basic rule of thumb is to check the size guide; that’s available for all shoes in this list.

Check the Cushioning Type

Choose shoes with max cushioning, such as gel, foam, or air, to absorb shock and reduce pressure on the feet. Luckily, all shoes on this list have enough cushioning.

This can help to alleviate neuropathy symptoms and make running more comfortable.

Benefits of Buying the Best Running Shoes for Neuropathy

Neuropathy Running Shoes on the table
  • Running shoes designed for neuropathy offer extra cushioning and support to reduce running discomfort and pain.
  • They provide support and stability to prevent ankle sprains and other running injuries.
  • They can reduce the impact on feet, helping to prevent blisters, calluses, and other foot problems.
  • Running shoes designed for neuropathy can improve traction and support, allowing for faster and further running.
  • They can reduce muscle fatigue caused by neuropathy and allow longer distances to run.
  • They offer support and stability, making it easier to maintain balance while running and reducing the risk of falls and injuries.
  • They often come with customizable fit options, making preventing blisters and other issues caused by poorly fitting shoes easier.
  • They are designed with breathable materials to keep feet cool and dry while running, reducing discomfort and irritation.
  • They provide excellent shock absorption, reducing the impact on feet while running and preventing joint pain and muscle fatigue.
  • Properly fitting running shoes can reduce the risk of developing injuries such as shin splints, plantar fasciitis, and Achilles tendonitis, ensuring that runners stay healthy and protected while achieving their fitness goals.

In Conclusion

When you suffer from neuropathy, everything comes down to safety and comfort. But should conditions like this stop you from staying healthy? Losing that therapeutic run? Absolutely not. After all, running will be much safer with Orthofeet Lava (for men) or Coral (for women); you see why it is so.

Everyone here at ExtremeHealthGuides is always wishing you the fastest recovery. On top of that, happy running!


Yes, athletic shoes for neuropathy are effective for controlling pain, allowing for safe and comfortable movement.

Yes, jogging is beneficial for neuropathy as it helps to increase movement and heart rate, both of which are important for people with neuropathy.

Yes, it is possible to run with peripheral neuropathy. To do so safely, it is important to have the right shoes designed specifically for running with neuropathy.

Orthofeet Lava
Arch support
Toe box







Overall Score


visa, master, amex & paypal logos
Protective toe box reduces pressure on the feet and toes
Cushioned insole provides customized support and cushioning
Lightweight sole reduces the impact on feet and legs during exercise
Breathable upper to maintain temperature
Excellent arch support for improved balance
Get the BEST PRICE until the end of July
Limited color options

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Milner Bradley
Milner Bradley has had over 15 years of experience in Health, Nutrition, research, and Journalism. His articles are extemely researched and experience and all the posts are verified by scientific findings. He shares his knowledge Here at Extreme Health Guides. Read more about us.

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